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How a Water Crisis Could Trigger the World's First Cyber War

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  As Turkey's Dams Hold back Tehran's Water When Geopolitical Leverage Meets Existential Desperation, the Desperate Actor Has One Final Card TL;DR Tehran faces evacuation within weeks as reservoir levels hit 11-13% capacity. Iran's water crisis—caused primarily by IRGC corruption and mismanagement, not climate change—could trigger unprecedented military escalation. Turkey controls 88-90% of Euphrates flow through its GAP cotton project (a deliberate Aral Sea-style disaster), while international law and organizations remain powerless due to sovereignty principles. Iran possesses both conventional missiles capable of destroying Turkish dams (potentially killing 50,000-500,000) and proven cyber capabilities to hack dam SCADA systems—a reversible, deniable alternative demonstrated when Iranian hackers penetrated a U.S. dam in 2013. Western media buries the story under "climate change" framing that obscures IRGC responsibility and prevents accountability. The inter...

NAD+ Restoration Reverses Alzheimer's Pathology in Mice

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Path to Human Treatment Remains Long and Uncertain BLUF (Bottom Line Up Front): Researchers at Case Western Reserve University have demonstrated that restoring brain NAD+ levels with the compound P7C3-A20 reversed Alzheimer's pathology and cognitive deficits in two distinct mouse models. The findings, published in Cell Reports Medicine, show comprehensive disease modification including restored memory, reduced inflammation, and repaired blood-brain barrier function in mice with advanced disease. While parallel human tissue analyses confirm NAD+ disruption in Alzheimer's, the work remains preclinical, and substantial biological, regulatory, and clinical hurdles separate mouse recovery from human therapy. In a windowless laboratory at Case Western Reserve University, mice genetically engineered to develop Alzheimer's disease demonstrated something remarkable: after 12 weeks of treatment with a small molecule drug, they navigated mazes with the precision of healthy animals...

The Great Prostate Biopsy Debate: Transperineal vs. Transrectal

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– What the Evidence Really Shows Prostate Biopsy Methods: Why America Lags Behind on Safety and Accuracy While Economic Interests Override Evidence TL;DR: Transperineal (TP) prostate biopsies are safer and more accurate than transrectal (TR) biopsies, detecting 6% more cancers while virtually eliminating life-threatening infections. Europe and Australia switched to TP as the standard in 2021, citing infection prevention and antimicrobial stewardship. Yet U.S. guidelines still call both methods "equivalent" despite mounting evidence. The resistance to change stems from powerful economic and workflow incentives: TR biopsies are faster, more profitable for office-based practices, and don't require costly equipment upgrades. Meanwhile, claims that TR is "more cost-effective" ignore massive downstream costs including antibiotic resistance and sepsis treatment. For Active Surveillance patients requiring repeated biopsies over years, the choice between methods could ...